PROGRAMAS DE ACTIVIDADES DE I+D EN BIOMEDICINA, ENTRE GRUPOS DE INVESTIGACIÓN DE LA COMUNIDAD DE MADRID

Convocatoria 2010 - S2010/BMD-2439 - VISIONANIMAL-CM                               

ANIMAL MODELS FOR THE STUDY OF VISION DISORDERS

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OBJETIVES

Objetive 1: Analyze the genetic basis and the underlying cellular mechanisms associated to myopia, experimentally induced, particularly in animal models of albinism

Groups involved: Jaime Tejedor, Pedro de la Villa, Lluís Montoliu, Anna González

Objetive 2: Establish the role of L-DOPA in the restoration of the visual deficits that are characteristic of animal models of albinism and the assessment of its potential therapeutical use

Groups involved: Lluís Montoliu, Pedro de la Villa, Jaime Tejedor

Objetive 3: Cloning the gene/locus associated with a possible new animal model of age-related macular degeneration (AMD)

Groups involved: Lluís Montoliu, Pedro de la Villa, Anna González, Jaime Tejedor

Objetive 4: Obtaining new animal models, mice, where to functionally assess the inactivation of Pomt1 gene in the retina, thus describing the visual phenotype associated to distroglycanopathies

Groups involved: Jesús Cruces, Lluís Montoliu, Pedro de la Villa, Anna González, Jaime Tejedor

 RESEARCH TOPICS

Animal models by genetic manipulation (Lluís Montoliu, CNB-CSIC)

Human Genotyping Unit (Anna González-Neira, CNIO)

Animal Models for the study of distroglycanopathies in vision (Jesús Cruces, IIBm UAM/CSIC)

Visual Neurophysiology (Pedro de la Villa, UAH)

Ophthalmology (Jaime Tejedor, Fund. Ramón y Cajal)

webmaster: Lluís Montoliu (CNB-CSIC)