Huseyin Tas

I received my B.Sc. in Biological Sciences and Bioengineering at Sabanci University, Turkey (2012) and received my M.Sc. in Biophysics and Computational Biology at University of Illinois Urbana-Champaign, USA (2014). During my Masters, I worked on developing genomic manipulation techniques for precise bacterial genome editing (for details see also: Tas et al, PLoS One, 2015). Having completed my Masters, I have become more interested in Synthetic Biology and its applications and now I am doing my PhD studies in this field under the advisory of Prof. VĂ­ctor De Lorenzo at Consejo Superior de Investigaciones y Ciencias (CSIC, Madrid).

In De Lorenzo Lab, I am mainly working on programming bacterial genome (specifically Pseudomonas putida). This concept includes building artificial pathways and organizational circuitries in the bacterial genetic information in order to provide Action-of-Interest. This is done through implementing genetic circuits based on Boolean logic. The concept is not only important for incorporating the idea of biosensors in an applicable platform especially for the environmental systems, but also important for the proof of concept for the future programmable robotic bugs.


However, this system has some bottlenecks. Synthetic Biology is a field that has been an attention magnet especially for the last two decades. Although, there have been numerous valuable inputs into the field, still we are lacking of having better standards in order to build comprehensive systems. This is in mind, I am working on Standardization of P. putida. As the motivation of having standards is to enable Putida to be a robust platform for genomic modifications, my aim is to bring universal standards for Putida and synthetic biology compounds.

To sum up, having a standardized platform furnished with point-of-interest biosensors integrate-able to Putida that can sense, process and react to its environment is my ultimate goal.

For further details about myself, you can also check my personal web page.