The Poxvirus and Vaccine Laboratory is a partner in MVACTOR (Host immune activation
optimized vaccinia virus vectors for vaccine development),
a project funded through the 6th Framework Programme of the European Union which aims on the development of new generation potent viral
vector vaccines with optimised host immune-activating properties based on the highly attenuated modified vaccinia virus Ankara (MVA).
Prof. Esteban's lab is collaborating in the development of a European Vaccine Against HIV/AIDS, a project funded by the European Union (EU) and is a founding member of
Prof. Esteban's lab is collaborating in the Poxvirus T-cell Vaccine Discovery Consortium (PTVDC), a project aimed at developing a vaccine against HIV/AIDS based on optimizing the immunogenicity of the poxvirus vectors MVA and NYVAC, funded by the Bill & Melinda Gates Foundation.
Prof. Esteban's lab is developing poxvirus vaccines against prevalent human diseases, like HIV/AIDS, leishmaniasis, hepatitis C and prostate cancer, a project funded by Foundation Botín.
Prof. Esteban's lab is collaborating with clinical centers in Spain in a phase I study examining the safety and immunogenicity in healthy human volunteers of the HIV/AIDS vaccine candidate MVA-B (expressing the HIV-1 antigens from clade B, Env/Gag-Pol-Nef) developed at the CNB.
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